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Combination Cancer Therapy: Modulators and Potentiators (Cancer Drug Discovery and Development)

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Expert physician-scientists and clinicians review those combinations of novel target agents classic chemotherapies that hold the most promise for the future of medical oncology, and detail their optimal sequence, pharmacokinetic interactions, and interaction with downstream cellular signals. The combinations run the gamut of targeted therapies against cell surface receptors (EGF-R and HER2), the cell cycle (the CDKs), signal transduction events (PKC and NF-kB), apoptosis (bcl-2), as well as focused therapies in ovarian cancer, hematologic diseases, and breast cancer. The authors emphasize novel translational approaches that are rapidly moving from the laboratory bench top to the patient's bedside for the future treatments in cancer therapy.

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Database Annotation in Molecular Biology: Principles and Practice
Database Annotation in Molecular Biology: Principles and Practice
Two factors dominate current molecular biology: the amount of raw data is increasing very rapidly and successful applications in biomedical research require carefully curated and annotated databases.  The quality of the data - especially nucleic acid sequences - is satisfactory; however, annotations depend on features inferred from the data...
Mathematics of Economics and Business
Mathematics of Economics and Business
Today, a firm understanding of mathematics is essential for any serious student of economics. Students of economics need nowadays several important mathematical tools. These include calculus for functions of one or several variables as well as a basic understanding of optimization with and without constraints, e.g. linear programming plays an...
Ring Theory And Algebraic Geometry (Lecture Notes in Pure and Applied Mathematics)
Ring Theory And Algebraic Geometry (Lecture Notes in Pure and Applied Mathematics)

Focuses on the interaction between algebra and algebraic geometry, including high-level research papers and surveys contributed by over 40 top specialists representing more than 15 countries worldwide. Describes abelian groups and lattices, algebras and binomial ideals, cones and fans, affine and projective algebraic varieties, simplicial and...


Sleep Medicine: A Guide to Sleep and its Disorders
Sleep Medicine: A Guide to Sleep and its Disorders

On average people spend one third of their life sleeping. An understanding of the physiology and pathophysiological changes that take place during this time is, therefore, essential to the medical care of patients. Sleep disorders can arise from a variety of causes including respiratory, psychiatric and neurological conditions, as well as...

Digital Design (VHDL): An Embedded Systems Approach Using VHDL
Digital Design (VHDL): An Embedded Systems Approach Using VHDL

This book provides a foundation in digital design for students in computer engineering, electrical engineering and computer science courses. It deals with digital design as an activity in a larger systems design context. Instead of focusing on gate-level design and aspects of digital design that have diminishing relevance in a...

Delmar's Handbook of Essential Skills and Procedures for Chairside Dental Assisting
Delmar's Handbook of Essential Skills and Procedures for Chairside Dental Assisting

This book provides essential information on the core clinical skills and procedures dental assistants need to know. Concise and user friendly, it presents a learning system appropriate for formal education settings, lab-based programs, on-the-job training and refresher courses, as well as chairside reference. Outstanding illustrations make...

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