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The current demand for the development of techniques for controlled genetic manipulations is driven by the anatomical and physiological complexity of the brain and by the need for experimental models that can address this complexity through selective manipulation of defined components of the system: specific neuronal populations or selected synapses. In Controlled Genetic Manipulations, expert researchers present detailed chapters to supply basic technical information about controlled genetic manipulations and to provide examples of creative implementation of this methodology when addressing a unique biological problem. Some chapters of the book describe the most recent developments in the basic methodology, which includes use of Cre-recombinase, methods for delivery of genetic material into the brain and the use of optogenetics, whereas other chapters focus on applying these techniques to addressing particular biological questions like structural and functional mapping of neuronal circuits, analysis of specific synaptic connections, modeling or gene therapy of neurological disorders. As part of the Neuromethods series, chapters include key implementation advice that is crucial for getting optimal results.
Authoritative and practical, Controlled Genetic Manipulations serves as a valuable guide to a variety of techniques, provided by many of the pioneers of the approaches. |
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 Adobe Captivate 4: The Definitive Guide
Adobe Captivate 4: The Definitive Guide, the follow-up to Wordware s popular Adobe Captivate 3: The Definitive Guide, steps you through all the procedures needed to create Flash movies based on any software on your desktop. You ll learn how to create Flash movies, edit individual screens, add and edit sound, even add interactivity (with or... | | Philosophy After Deleuze (Deleuze Encounters)
Philosophy After Deleuze providesa concise and accessible introduction to Deleuze in relation to philosophicalinquiry. The book shows how Deleuze's work contributes to contemporary debatesin each of the major areas of philosophy: metaphysics, ethics, aesthetics, andpolitical philosophy. Hughes begins by examining Deleuze's style,... | | Manage Your Money and Investments with Microsoft ExcelSure you want to save money. We all do. But saving money is sometimes easier said than done. Did you know that there is a program probably already installed on your computer that can help you manage your money better? It's Microsoft Excel, part of the Microsoft Office suite. Manage Your Money and... |
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