|
Pancreatic ductal adenocarcinoma is the fourth leading cause of cancer
death in the United States. Annually approximately 30,000 Americans are
diagnosed with the disease and most will die from it within five years. Pancreatic
ductal adenocarcinoma is unique because of its late onset in age, high
mortality, small tumor samples infiltrated with normal cells, and a lack of
both early detection and effective therapies. Some of these characteristics
have made studying this disease a challenge.
Pancreatic cancer develops as a result of the accumulation of genetic
alterations in cancer-causing genes, such as the oncogenes and the tumor-suppressor
genes. In the last decade, major progress has been made in identifying
important oncogenes and tumor-suppressor genes for the disease. In Pancreatic
Cancer: Methods and Protocols, we review the classical techniques that
have contributed to the advances in pancreatic research and introduce new
strategies that we hope will add to future breakthroughs in the field of cancer
biology.
Pancreatic Cancer: Methods and Protocols provides a broad range of
protocols for molecular, cellular, pathological, and statistical analyses of sporadic
and familial pancreatic cancer. It covers topics from in vitro cell cultures
to in vivo mouse models, DNA to protein manipulation, and mutation
analyses to treatment development. We believe that our book will prove an
invaluable source of proven protocols for those who are interested in either
basic or translational research in pancreatic cancer. |
|
|
 Digital Character Animation 3Whether you're creating animation for television, advertising, games, or multimedia, [digital] Character Animation 3 can help you bring your imagination to life. In this updated classic, both newcomers to digital animation and old hands looking to hone existing skills will find essential techniques for creating... | | CISSP All-in-One Exam Guide, 6th Edition
A complete, up-to-date revision of the leading CISSP training resource from the #1 name in IT security certification and training, Shon Harris
Fully revised for the latest release of the Certified Information Systems Security Professional exam, this comprehensive, up-to-date resource covers all 10 CISSP exam domains developed by... | | |
|
