Reports on the latest advances in the field, for new and experienced scientists. Coverage includes the role of T-cells in multiple sclerosis (MS), T-cell autoimmunity and EAE in nonhuman primates, MBP-reactive T-cells in MS, and genetic engineering of brain-specific T-cells for treatment of diseases in the central nervous system. Also discussed are T-cells and cytokines, cytokines in MS and its experimental models, antigen-specific T-cell responses in autoimmune demyelinating disease, and immunopathogenesis of MS. The editor is affiliated with the Kennedy Institute of Rheumatology, UK. Annotation c. Book News, Inc., Portland, OR (booknews.com)