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Over the last 15 years, apoptosis has become a dominant focus of medical research in the field of immunology. This publication discusses the three major areas of apoptosis research: extrinsic death receptor pathways, intrinsic cell death pathways and the mechanisms responsible for apoptotic cell clearance. Each section delineates the proteins and signal transduction pathways and describes genetic alterations that lead to autoimmune diseases. Although most cell death abnormalities have been associated with systemic autoimmune disorders such as lupus erythematosus and lymphoproliferative syndromes, it is evident that regulation of cell death is also pertinent to disease expression in many organ-specific diseases such as rheumatoid arthritis and glomerulonephritis.This volume highlights the recent advances in the basic mechanisms of apoptosis and the application of that knowledge to understanding the impact of defective apoptosis or defective clearance of apoptotic cells on the immune function and the expression of disease. It is of special interest to cell biologists, immunologists and clinicians. |
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Server Load BalancingThis book is meant to be a resource for anyone involved in the design, production, overseeing, or troubleshooting of a site that employs server load balancing (SLB). Managers and other high-level people can use this book to improve their understanding of the overall technology. Engineers and site architects can use this book to give insight into... | | Wireless Transceiver Systems DesignThis book brings together the fields of communication, signal processing, and embedded systems and circuits. These fields come together with a single design goal, a WLAN transceiver which combines analog and digital design, VLSI and systems design, algorithms and architectures, as well as design and CAD/EDA. This book focuses on the overall... | | C Programming - An Advanced Course
This book takes up where C Programming - A Beginner's Course leaves off. It assumes you have a working knowledge of basic programming concepts such as variables, constants, assignment, selection (if..else) and looping (while, for). It also assumes you are comfortable with writing functions and working with arrays. If you are not, it is... |
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