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Between the Lines of Genetic Code: Genetic Interactions in Understanding Disease and Complex Phenotypes

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Between the Lines of Genetic Code lays out methodologies and tools for the measurement and evaluation of gene-gene and gene-environment studies and gives perspective on the future of this discipline. The book begins by defining terms for interaction studies, describing methodologies, and critically assessing the viability of current study designs and the possibilities for integrating designs. It then provides recent applications data with case studies in rheumatoid arthritis, multiple sclerosis, myositis and other complex human diseases. Last, it examines current studies and directions for future applications in patient care.

Recent multivariate studies show that gene-gene and gene-environment interactions can explain significant variances in inheritance that have previously been undetectable in univariate analysis. These links among genes and between genes and their environments during the development of diseases may serve as important hints for understanding pathogenic mechanisms and for developing new tools for prognosis, diagnosis, and treatment of various diseases.

  • Systematically integrates methods of defining and detecting gene interactions to provide an overview of the field
  • Critically analyzes current methods and tools to aid researchers in integrating gene interaction studies
  • Includes examples of current biomedical applications and presents current research expected to shape clinical research in the near future
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Mobile Marketing For Dummies
Mobile Marketing For Dummies

Marketers are always looking to make their communications more personal, more targeted, and more relevant. Mobile is arguably the most personal, targeted, and relevant marketing channel available.

Mobile devices provide individuals with almost instant access to friends and family, location-based information, productivity tools,...

Extreme Programming for Web Projects
Extreme Programming for Web Projects

Web development teams have been operating in the dark for far too long. The lack of proven development methodologies for the Web environment has resulted in a constant struggle for developers to produce quality Web-based projects on time and within budget. The field is multidisciplinary in character, involving both technology and...

Perspective Drawing in Adobe Illustrator CS5
Perspective Drawing in Adobe Illustrator CS5
This book is intended for users of Adobe Illustrator CS5. It describes the basics of linear perspective and discusses in detail the feature set available in Illustrator CS5 for drawing a scene in perspective.

Adobe Illustrator CS5 offers a completely new form of vector drawing— perspective or
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The Complete Guide to Buying and Selling Apartment Buildings
The Complete Guide to Buying and Selling Apartment Buildings
The systematic acquisition of real estate properties over time is unquestionably
one of the surest means of accumulating wealth. While building a
respectable real estate portfolio is a process that can take months, or even
years, the patient and diligent investor enjoys a high probability of earning
above-average returns for his
...
The Art of Computer Programming. Vol 1: Fundamental Algorithms. 2nd Printing.
The Art of Computer Programming. Vol 1: Fundamental Algorithms. 2nd Printing.

Fundamental Algorithms begins with mathematical preliminaries. The first section offers a good grounding in a variety of useful mathematical tools: proof techniques, combinatorics, and elementary number theory. Knuth then details the MIX processor, a virtual machine architecture that serves as the programming target for subsequent...

Mobile IP Technology for M-Business
Mobile IP Technology for M-Business
Here's a first-of-its-kind book that introduces you to the next generation of mobile networks, where IP data capability and mobile communications become integrated to form new, cutting-edge Mobile IP networks. This unique resource offers you a thorough understanding of the convergence of mobile and data technology. It explains how the prospect of...
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