In the latter part of the 20th century, hematologists and medical oncologists
were trained to treat leukemia with systemic therapy that was cytotoxic to both
normal and malignant cells. Some of these therapies, such as methotrexate and
L-asparaginase, were developed within the context of known biologic pathophysiology,
but most were developed in relative ignorance of biologic mechanisms
and cannot therefore be considered “biologic.” The usual goal of treatment
was to eliminate rapidly dividing, or malignant, cells with DNA-damaging agents
that spared normal tissue only in a relative sense.
Exciting new "biologic" therapies for treating leukemia are appearing so rapidly that clinicians often find it difficult to make informed decisions about their use when making patient treatment decisions. Biologic Therapy of Leukemia summarizes and reviews all the available data concerning these cutting-edge biologic therapies so that practicing clinicians can make the correct patient-care choices. Here the busy physician will find in one convenient place crucial information on the uses and limitations of the major biologic therapies for leukemia, the different biologic strategies for its treatment, the management of patients being treated with such biologic agents, and the current and future role of emerging biologic agents.
GSM & UMTS: The Creation of Global Mobile Communications GSM (Global System for Mobile communication) provides a service to more than 500 million users throughout 168 countries worldwide. It is the world market leader serving 69 0f all mobile digital users and is currently evolving into UMTS (Universal Mobile Telecommunication System).
By describing the critical decisions and the phases of the...
Data Engineering: Fuzzy Mathematics in Systems Theory and Data Analysis
Although data engineering is a multi-disciplinary field with applications in control, decision theory, and the emerging hot area of bioinformatics, there are no books on the market that make the subject accessible to non-experts. This book fills the gap in the field, offering a clear, user-friendly introduction to the main theoretical and...
MOS 2010 Study Guide for Microsoft Word, Excel, PowerPoint, and Outlook
Desktop computing proficiency is increasingly important in today’s business world. As a result, when screening, hiring, and training employees, employers can feel reassured by relying on the objectivity and consistency of technology certification to ensure the competence of their workforce. As an employee or job seeker, you can...
Aston University 'Branding' Bundle: Creating Powerful Brands, Fourth Edition
As we look forward with confidence that this new edition significantly benefits
students and managers, we look back to how this book became a well established
core text in many business schools internationally and amongst a lot of
managers. It seems not that long ago when we embarked on this project, yet as
our publisher... Windows 7 Annoyances: Tips, Secrets, and Solutions
They say no one should see how sausage or laws get made, and I feel the same
is true for software.
Imagine a windowless room in a nondescript office building. Inoffensive tan carpet lines the floors, fluorescent lights hum softly overhead, and 20 seated Microsoft employees flank a rectangular folding table in the center of...