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Biomarkers in Breast Cancer (Cancer Drug Discovery and Development)

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Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.

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Skeletal Trauma: Fractures, Dislocations, Ligamentous Injuries (2-Volume Set)
Skeletal Trauma: Fractures, Dislocations, Ligamentous Injuries (2-Volume Set)
The first edition of Skeletal Trauma: Fractures, Dislocations, Ligamentous Injuries was written between 1988 and 1991. This represented a unique window for the creation of this text, coinciding with the increased recognition of the special needs of trauma victims. By the mid-1980s, more than 500 regional trauma centers had...
Mastering VMware vSphere 5.5
Mastering VMware vSphere 5.5

The 2013 edition of the bestselling vSphere book on the market

Virtualization remains the hottest trend in the IT world, and VMware vSphere is the industry's most widely deployed virtualization solution. The demand for IT professionals skilled in virtualization and cloud-related technologies is great and expected to keep...

Learning Spring Application Development
Learning Spring Application Development

Develop dynamic, feature-rich, and robust Spring-based applications using the Spring Framework

About This Book

  • Build and deploy Spring-powered, production-grade applications and services with minimal fuss
  • Discover the key Spring framework-related technology standards such as Spring core,...

Models, Methods, and Tools for Complex Chip Design: Selected Contributions from FDL 2012
Models, Methods, and Tools for Complex Chip Design: Selected Contributions from FDL 2012
This book is the latest contribution to the LNEE series, and it consists of selected papers presented at the Forum on Specifications and Design Languages (FDL) 2012, which took place in September 2012 at Vienna University of Technology, Vienna, Austria.

FDL is a well-established international forum devoted to
...
Camera Networks: The Acquisition and Analysis of Videos over Wide Areas (Synthesis Lectures on Computer Vision)
Camera Networks: The Acquisition and Analysis of Videos over Wide Areas (Synthesis Lectures on Computer Vision)
Camera networks is a highly interdisciplinary area of research that has been very active over the last few years. In this book, we focus specifically on the topic of video understanding in camera networks and touch upon the other related areas (e.g., communication resources, machine learning, cooperative control of multi-agent...
Real-World Hadoop
Real-World Hadoop

If you’re a business team leader, CIO, business analyst, or developer interested in how Apache Hadoop and Apache HBase-related technologies can address problems involving large-scale data in cost-effective ways, this book is for you. Using real-world stories and situations, authors Ted Dunning and Ellen Friedman show Hadoop...

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