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Brain Metastases (Cancer Treatment and Research)

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Brain metastases are among the most feared and debilitating complication of systemic cancer. They impact approximately 170 000 patients a year in the United States, a number ten-fold greater than malignant gliomas. Historically, brain metastases were diagnosed in patients with widespread systemic malignancy. Recent improvements in systemic therapies are changing the incidence of brain metastases.

More patients are being diagnosed with brain metastases in the setting of controlled systemic tumor.

In this book we provide succinct and up-to-date information to help manage cancer patients who have the misfortune to develop brain metastases. A multidisciplinary assessment involving neurosurgery, radiation oncology, neuro-oncology and medical oncology is critical to optimize patient management and outcome.

While average survival remains poor, recent advances in surgery, radiation and chemotherapy may improve disease control and quality of life for many patients. We hope this book will not only serve as a reference for practitioners in oncology but also stimulate ideas for future research.
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Supervisory Control of Concurrent Systems: A Petri Net Structural Approach (Systems & Control: Foundations & Applications)
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Information Warfare and Organizational Decision-Making
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Organizations are among the most valuable and yet most fragile structures of our civilization. We rely on organizations to obtain information, to comprehend and process information, to accumulate and internalize information, to make decisions based in part on that information, and to execute those decisions. Organizations are ubiquitous because...
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