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Camptothecins in Cancer Therapy (Cancer Drug Discovery and Development)

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A critical review our current understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional chapters describe what is known about the biochemistry, the pharmacology, and the chemistry of the camptothecins, including the mechanism of topoisomerase and how camptothecins poison this enzyme, the use of animal models in defining the anticancer potential of camptothecins, and the question of camptothecin resistance.

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Beginning Game AI with Unity: Programming Artificial Intelligence with C#
Beginning Game AI with Unity: Programming Artificial Intelligence with C#
Among all the technologies that have been flourishing in the last decade, there is one that is becoming essential for our society and it’s enhancing all the other tech fields as well as every aspect of our life: Artificial Intelligence (AI). From navigation systems to smart cars and from virtual assistants to augmented...
A Practical Guide to Graphics Reporting: Information Graphics for Print, Web & Broadcast
A Practical Guide to Graphics Reporting: Information Graphics for Print, Web & Broadcast

A Practical Guide to Graphics Reporting explains all of the most important skills and theoretical considerations for creating diagrams, charts, maps, and other forms of information graphics intended to provide readers with valuable visual and textual news and information.

Research and writing skills as
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Eclipse in Action: A Guide for the Java Developer
Eclipse in Action: A Guide for the Java Developer
"The technical information is dead on...I'd definitely recommend this book to anyone."

This book is a fast-paced but thorough guide to the effective use of Eclipse's features and plugins for real-world Java development. Interesting examples demonstrate how to use Eclipse to build, test, and debug applications using
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Image Processing with ImageJ
Image Processing with ImageJ

Discover the incredible possibilities of ImageJ, from basic image processing to macro and plugin development

Overview

  • Learn how to process digital images using ImageJ and deal with a variety of formats and dimensions, including 4D images
  • Understand what histograms, region of interest, or...
Learn FileMaker Pro 9 (Wordware Library for FileMaker)
Learn FileMaker Pro 9 (Wordware Library for FileMaker)
This is meant to be a hands-on book. The idea is to have you do various exercises so that you become familiar with FileMaker Pro. The book doesn’t have that much to do with theory, although you will learn some along the way. There are other books for theory, if that’s something you care about.

The FileMaker Pro PDF manual
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100 Simple Secrets of the Best Half of Life: What Scientists Have Learned and How You Can Use It
100 Simple Secrets of the Best Half of Life: What Scientists Have Learned and How You Can Use It

Practical advice on how to thrive in the second half of your life, based on scientific studies. The sixth book in the bestselling 100 Simple Secrets series.

What do people who relish the second half of their lives do differently than those who dread getting older? Sociologists, therapists and psychiatrists have spent entire careers...

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