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Cancer Chemoprevention: Volume 1: Promising Cancer Chemopreventive Agents (Cancer Drug Discovery and Development) (v. 1)

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A comprehensive reference survey on the identification and development of promising cancer chemopreventive agents that will help stimulate further novel research and new approvable drugs. For each agent, the authors review the relevant mechanisms of action, the criteria for populations benefiting from intervention, the safety and pharmacodynamics, clinical study design emphasizing the use of precancers, and early associated cellular and molecular biomarkers of carcinogenesis. The pharmacologic and/or mechanistic classes discussed range from antimutagens, antiinflammatories, and the nuclear receptor superfamily, to signal transduction modulators, antioxidants, vitamins, and minerals. The overall focus is on molecular targets and mechanisms. A second volume, Strategies in Chemoprevention, describes the exciting methodologies that will accelerate progress in this field and discusses the state of clinical development of chemoprevention in the various human cancer target organs.

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Confessions
Confessions
"Williams's masterful translation satisfies (at last!) a long-standing need. There are lots of good translations of Augustine's great work, but until now we have been forced to choose between those that strive to replicate in English something of the majesty and beauty of Augustine's Latin style and those that opt instead...
Hands-On Microservices with Rust: Build, test, and deploy scalable and reactive microservices with Rust 2018
Hands-On Microservices with Rust: Build, test, and deploy scalable and reactive microservices with Rust 2018

A comprehensive guide in developing and deploying high performance microservices with Rust

Key Features

  • Start your microservices journey and get a broader perspective on microservices development using RUST 2018,
  • Build, deploy, and test microservices using AWS
  • ...
Plato and the Divided Self
Plato and the Divided Self

Plato's account of the tripartite soul is a memorable feature of dialogues like the Republic, Phaedrus and Timaeus: it is one of his most famous and influential yet least understood theories. It presents human nature as both essentially multiple and diverse - and yet somehow also one - divided into a fully human 'rational' part, a...


Electrocatalysis in Fuel Cells: A Non- and Low- Platinum Approach (Lecture Notes in Energy)
Electrocatalysis in Fuel Cells: A Non- and Low- Platinum Approach (Lecture Notes in Energy)

Fuel cells are one of the most promising clean energy conversion devices that can solve the environmental and energy problems in our society. However, the high platinum loading of fuel cells - and thus their high cost - prevents their commercialization.  Non- or low- platinum electrocatalysts are needed to lower the fuel cell...

Encyclopedia of the Hundred Years War
Encyclopedia of the Hundred Years War

Provides clear, concise, and basic descriptions and definitions to over 260 key people, events, and terms relating to the series of conflicts between France and England in the 14th and 15th centuries that later came to be known as the Hundred Years War.

The Encyclopedia of the Hundred Years War provides its users with clear,...

Optimization of Structures and Components (Advanced Structured Materials)
Optimization of Structures and Components (Advanced Structured Materials)

Written by an international group of active researchers in the field, this volume presents innovative formulations and applied procedures for sensitivity analysis and structural design optimization. Eight chapters discuss subjects ranging from recent developments in the determination and application of topological gradients, to the use of...

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