Having first decided to organize and edit a book on heart failure in 1992 (with a 1994 publication date), we have been astounded at the changes in the field over a relatively brief 14-year period. It is with some amusement that we now look back at our first edition and note a combined chapter of beta agonists and antagonists, a separate chapter on phosphodiesterase inhibitors, and an extensive discussion of antiarrhythmic therapy in congestive heart failure (CHF) with only a brief mention of implantable defibrillators. On the other hand, it is somewhat disheartening to see that the majority of our advances over this period have come from very generic approaches to CHF, with much less progress in interfering with underlying etiologies. Nonetheless, we continue to move forward on a broad front with an expanded view of the genetics of primary cardiac muscle disease, better imaging techniques, routine screening blood testing, and standardization of medical management. We have the addition of new agents to the therapeutic armamentarium, widespread use of prophylactic defibrillators, and several novel approaches, including biventricular pacing, continuous flow ventricular assist technology, and cellular transplantation.

 

The fact that both our understanding and treatment of heart failure continue to evolve at a rapid rate is the real motivation that led us to move forward with the third edition of Congestive Heart Failure. As with the first two editions, the aim is to provide a comprehensive overview of heart failure and to point out areas where future advances are likely. Again, the text is geared to both the scientist and clinician with the hope that each will find the broad base of information valuable in some way in their respective daily activities.

 

We would like to acknowledge the excellent contributions of our authors, who not only supplied these chapters in a timely fashion but who were so responsive to editorial comments and revisions. Their professionalism, inquisitiveness, and enthusiasm made our role a joy rather than a burden. Finally, the loving support and encouragement of our families in this and all our other professional endeavors has been instrumental in whatever success we have achieved.