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Death Receptors in Cancer Therapy (Cancer Drug Discovery and Development)

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An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling in melanoma, synthetic retinoids and death receptors, the role of p53 in death receptor regulation, immune suppression of cancer, and combination therapy with death ligands.

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Organic Chemistry Demystified
Organic Chemistry Demystified
Take the unCONQUERability out of ORGANIC CHEMISTRY!

Now anyone can master organic chemistry -- without tears, unlimited time, or a Ph.D. In Organic Chemistry Demystified, organic chemist and experienced teacher Daniel Bloch provides an effective and painless way to learn or review organic chemistry, from the chemical...

Model Driven Engineering Languages and Systems: 10th International Conference, MoDELS 2007, Nashville, USA, September 30 - October 5, 2007, ... / Programming and Software Engineering)
Model Driven Engineering Languages and Systems: 10th International Conference, MoDELS 2007, Nashville, USA, September 30 - October 5, 2007, ... / Programming and Software Engineering)

This book constitutes the refereed proceedings of the 10th International Conference on Model Driven Engineering Languages and Systems (formerly the UML series of conferences), MODELS 2007, held in Nashville, USA, September 30 - October 5, 2007. The 45 revised full papers were carefully reviewed and selected from 158 initial submissions. The...

Handbook Of Pi And Pid Controller Tuning Rules
Handbook Of Pi And Pid Controller Tuning Rules

The vast majority of automatic controllers used to compensate industrial processes are PI or PID type. This book comprehensively compiles, using a unified notation, tuning rules for these controllers proposed from 1935 to 2008. The tuning rules are carefully categorized and application information about each rule is given. This book discusses...


The UMTS Network and Radio Access Technology: Air Interface Techniques for Future Mobile Systems
The UMTS Network and Radio Access Technology: Air Interface Techniques for Future Mobile Systems
The UMTS Network and Radio Access Technology covers all the key aspects of UMTS and its implementation from both the engineering design and the operator and service providers' point of view. It addresses the essential tasks involved in UMTS network deployment in new regions and within existing 2G networks. Presenting solutions for the...
Crystal Reports 9 on Oracle
Crystal Reports 9 on Oracle
Create dynamic, effective reports from Oracle databases using Crystal Reports 9 and the extensive information in this practical resource. Learn to use one of the most powerful data analysis tools to draw information from Oracle databases, query and rank data, consolidate results, and develop integrated, interactive reports. Plus, leverage the...
Finite Element Method Using MATLAB (Mechanical Engineering)
Finite Element Method Using MATLAB (Mechanical Engineering)
The finite element method (FEM) has become one of the most important and useful tools for scientists and engineers. This new book features the use of MATLAB to present introductory and advanced finite element theories and formulations. MATLAB is especially convenient to write and understand finite element analysis programs because a MATLAB...
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