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Death Receptors in Cancer Therapy (Cancer Drug Discovery and Development)

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An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling in melanoma, synthetic retinoids and death receptors, the role of p53 in death receptor regulation, immune suppression of cancer, and combination therapy with death ligands.

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The Handy Anatomy Answer Book (The Handy Answer Book Series)
The Handy Anatomy Answer Book (The Handy Answer Book Series)
Pick up a magazine or newspaper, turn on the radio or television, or access medical and health information on the Internet and you will find that the human body is definitely in the news. Artificial hearts, dietary supplements, stem cell research, genetic engineering, arthroscopic surgery, and many other intriguing subjects on human biology and...
Methodologies and Software Engineering for Agent Systems: The Agent-Oriented Software Engineering Handbook
Methodologies and Software Engineering for Agent Systems: The Agent-Oriented Software Engineering Handbook
With increasing acceptance of agent-based computing, a great deal of new research related to the identification and definition of suitable models, and techniques to support the development of complex Multiagent Systems (MAS) has emerged. This research generally identified as Agent-Oriented Software Engineering (AOSE), continually proposes new...
Model Engineering in Mixed-Signal Circuit Design: A Guide to Generating Accurate Behavioral Models in VHDL-AMS
Model Engineering in Mixed-Signal Circuit Design: A Guide to Generating Accurate Behavioral Models in VHDL-AMS
The purpose of Model Engineering in Mixed-Signal Circuit Design is - for the first time - to combine the main issues of the hardware description language VHDL-AMS aimed at model representation of mixed-signal circuits and systems, of characterization methods and tools for the extraction of model parameters, and of modeling...

Practical Web Development
Practical Web Development

Learn CSS, JavaScript, PHP, and more with this vital guide to modern web development

About This Book

  • Explore how the web is built from its foundations – learn everything from basic HTML through to JavaScript, PHP and beyond
  • Discover the latest trends in modern web development and...
Chemistry of Photography
Chemistry of Photography
Carried in wallets and displayed in homes, photographs are a common, but often an overlooked feature of modern life. And, with the advent of digital technology many believe that the so called 'wet chemistry' behind old fashioned photography is a thing of the past - but is it?

The Chemistry of Photography endeavours to unravel the mysteries of...

Real Estate Investing For Canadians For Dummies
Real Estate Investing For Canadians For Dummies

The past decade has seen many real estate investors taken on a wild ride. The first decade of the 21st century began with real estate being seen as a safe haven for investors, and the boom that followed made real estate the sure-fire key to wealth. The subprime mortgage crisis in the United States and drop in real estate values around the...

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