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Flow Cytometry in Hematopathology: A Visual Approach to Data Analysis and Interpretation (Current Clinical Pathology)

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Flow cytometry immunophenotyping of hematopoietic disorders is a complex and demanding exercise that requires a good understanding of cell lineages, developmental pathways, and physiological changes, as well as broad experience in hematopathology. The process includes several interrelated stages, from the initial medical decision regarding which hematologic c- dition is appropriate for FCM assay, to the final step of diagnosis whereby the FCM data is correlated with other relevant clinical and laboratory information. The actual FCM testing involves three major steps: pre-analytical (specimen processing, antibody staining), analytical (acquiring data on the flow cytometer) and post-analytical (data analysis and interpretation). The literature, including the latest FCM textbooks, provides ample information on the te- nical principles of FCM such as instrumentation, reagents and laboratory methods, as well as quality control and quality assurance. Similarly, correlations of morphologic findings and p- notypic profiles have been well covered in many publications. In contrast, much less attention has been given to the other equally important aspects of FCM immunophenotyping, especially data analysis. The latter is a crucial step by which a phenotypic profile is established. To bridge this gap in the literature, the focus of this book is more on FCM data analysis than laboratory methods and technical details. For the reader to become familiar with our data analysis strategy, an overview of our approach to the pre-analytical and analytical steps is also presented, with an emphasis on the pre-analytical aspects, which have been rarely touched upon in the literature.

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Financial Accounting: An Introduction to Concepts, Methods and Uses (Available Titles CengageNOW)
Financial Accounting: An Introduction to Concepts, Methods and Uses (Available Titles CengageNOW)

Ideal for graduate, MBA, and higher-level undergraduate programs, FINANCIAL ACCOUNTING: AN INTRODUCTION TO CONCEPTS, METHODS, AND USES presents both the basic concepts underlying financial statements and the terminology and methods that allows the reader to interpret, analyze, and evaluate actual corporate financial statements. Fully...

The Mathematics of Gambling
The Mathematics of Gambling

Casino card games such as baccarat and blackjack differ significantly from casino games such as craps, roulette, and slot machines in that they are not indepen- dent trial processes-that is, the cards that already have been played do affect the odds on subsequent hands. Consider for a moment the game of blackjack, where the cards...

Real Time UML: Advances in the UML for Real-Time Systems (3rd Edition)
Real Time UML: Advances in the UML for Real-Time Systems (3rd Edition)
The increasing complexity of embedded and real-time systems requires a more premeditated and sophisticated design approach for successful implementation. The object-based Unified Modeling Language (UML) can describe the structural and behavioral aspects critical to real-time systems and has come to the fore as an outstanding medium for effective...

CCNA Data Center - Introducing Cisco Data Center Networking Study Guide: Exam 640-911
CCNA Data Center - Introducing Cisco Data Center Networking Study Guide: Exam 640-911

A must-have study guide for exam 640-911 on Cisco's UnifiedData Center

The Cisco Certified Network Associate Data Center certificationis Cisco's newest certification, covering the Cisco Unified DataCenter technologies. Written by unparalleled author and Ciscoauthority Todd Lammle, and CCIE John Swartz, this...

SAS 9.1.3 Output Delivery System: User's Guide 2 VOL SET
SAS 9.1.3 Output Delivery System: User's Guide 2 VOL SET

The Output Delivery System (ODS) provides an almost limitless number of choices for reporting and displaying analytical results now with a greater variety of formatting selections and output destinations.

SAS 9.0, 9.1, and 9.1.3 provide an array of markup languages including HTML4 and XML. The TEMPLATE procedure and the new tagset...

Flexible Neuro-Fuzzy Systems : Structures, Learning and Performance Evaluation
Flexible Neuro-Fuzzy Systems : Structures, Learning and Performance Evaluation
Over the last decade fuzzy sets and fuzzy logic introduced in 1965 by
Lotfi Zadeh [113] have been used in a wide range of problem domains
including process control, image processing, pattern recognition and
classification, management, economics and decision making. Specific
applications include washing-machine automation,
...
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