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Gene Therapy of Cancer: Methods and Protocols (Methods in Molecular Medicine)

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Wolfgang Walther and Ulrike Stein survey the rapidly evolving field of cancer gene therapy and provide a broad array of leading-edge protocols for the delivery of therapeutic genes into tumors. Described in step-by-step fashion and enriched with each author's own practical tips, these readily reproducible methods are currently being widely applied in cancer gene therapy investigations, including immunotherapy and tumor vaccination, suicide gene therapy, antioncogene therapy, and antisense and ribozyme gene therapy. Representative strategies are provided for gene targeting and for viral or nonviral gene delivery in cancer therapy, as well as a significant number of clinical protocols for the development of novel cancer gene therapies. Gene Therapy of Cancer offers basic and clinical researchers a broad ranging overview and collection of the most recent advances in gene transfer techniques. Written by leading international authorities, the methods in this volume constitute today's most valuable tools for the study of cancer gene therapy in both the laboratory and clinical trials.

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Encyclopedia of Pain (3 volume set)
Encyclopedia of Pain (3 volume set)
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"Preparing such a mammoth book must have been a massive task. Two editors, 35 section editors and over 500 contributors … all took part. … All-in-all, this encyclopedia is an outstandingly useful resource for clinicians and scientists. … this book could be equally recommended to major...

Learning Drupal 6 Module Development
Learning Drupal 6 Module Development
Drupal is a highly successful open-source Content Management System (CMS). It is well‑respected for its robustness, its flexible and immaculate code, and its seemingly infinite capacity for extension and customization.

Drupal 6, released early in 2008, represents a significant evolution in this already mature CMS. In this book, we
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Professional Windows 8 Programming: Application Development with C# and XAML
Professional Windows 8 Programming: Application Development with C# and XAML
IT SEEMS LIKE YESTERDAY that Microsoft announced at its first annual BUILD conference the upcoming game-changing operating system: Windows 8. In the Microsoft world for the first time, Windows 8 was to provide an operating system that could create an ecosystem of apps that ran among phones, desktop computers, and tablets. Developers...

Developing Applications for the Cloud on the Microsoft Windows Azure Platform (Patterns & Practices)
Developing Applications for the Cloud on the Microsoft Windows Azure Platform (Patterns & Practices)

Windows Azure is a highly scalable, robust, and cost-effective solution for the deployment of applications and services—for organizations and enterprises of all sizes, and in all types of markets. My task at Microsoft is to ensure that developers can help these organizations and enterprises to achieve their goals by quickly and easily...

PC Interfacing and Data Acquisition: Techniques for Measurement, Instrumentation and Control.
PC Interfacing and Data Acquisition: Techniques for Measurement, Instrumentation and Control.
Until fairly recently most scientific data-gathering systems and industrial control procedures were based on electromechanical devices such as chart recorders and analogue gauges. The capability to process and analyse data was rather limited (and in some cases error prone) unless one had access to a minicomputer or mainframe. Today, that situation...
The Well Timed Strategy: Managing the Business Cycle for Competitive Advantage
The Well Timed Strategy: Managing the Business Cycle for Competitive Advantage

Most companies ignore one of their best opportunities for honing competitive advantage: the opportunity to proactively manage business cycles and macroeconomic turbulence. Despite the profound impact that the business cycle has on the fortunes and fate of so many businesses large and small--and the employees and investors...

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