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Handbook of Neurochemistry and Molecular Neurobiology: Neuroimmunology

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Neuroimmunology is one of the most rapidly developing branches of Neurobiology, prompted by novel neurochemical, neuroendocrinological, and neurophysiological investigations of the central and peripheral nervous system including neuroendocrine systems. Neuroimmunology can be considered as an interdisciplinary science that covers relevant aspects of how the peripheral immune system can influence brain physiology and elicit neuroendocrine immunoregulatory responses and also how local interactions between immune and neuronal mediators of the brain influence the occurrence and course of neuropathologic diseases. Therefore, we have in these volume chapters, focused on immune–neuro–endocrine interactions underlying the control and regulation of processes involved in both immune and brain physiology and in the pathogenesis of different nervous diseases. Among such diseases are: schizophrenia, HIV-associated dementia, rheumatoid arthritis, several experimental pathologies, multiple sclerosis, autoimmune encephalomyelitis, Theilers virus infection, nervous system demyelination diseases, the primary degenerative disorders such as Alzheimer’s and Parkinson’s as well as brain injuries resulting from stroke and trauma, the neuroimmunology of gene therapy, amyotrophic lateral sclerosis, Prion disease, and all theoretical questions covering these pathologies. All of the above-mentioned involve autoimmune processes.

Here is yet another of Springer s authoritative Major Reference Works. The release of these is a huge publishing event in itself, and this handbook on neurochemistry and molecular neurobiology is no exception. Required reading for neuroscientists and neurochemists, it contains data on multiple immunomodulators, many of which are also the products of hypothalamic brain cell neurosecretion. With contributions from dozens of researchers worldwide, and edited by two leading authorities in the field, this is information you can trust. Neuroimmunology is one of the most rapidly developing branches of Neurobiology, and this volume contains chapters that focus on a huge range of topics including the relationship between neuroimmunology and the pathogenesis of different nervous diseases.

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