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Heat Shock Proteins in Cancer

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Heat Shock Proteins in Cancer, 9781402064005 (1402064004), Springer, 2007

Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.

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Django: Web Development with Python
Django: Web Development with Python

About This Book

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  • Unravel the common problems of web development in Django
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Advanced Image Processing in Magnetic Resonance Imaging (Signal Processing and Communications)
Advanced Image Processing in Magnetic Resonance Imaging (Signal Processing and Communications)
Magnetic Resonance (MR) imaging produces images of the human tissues in a noninvasive manner, revealing the structure, metabolism, and function of tissues and organs. The impact of this image technique in diagnostic radiology is impressive, due to its versatility and flexibility in joining high-quality anatomical images with functional...
Essentials of Intellectual Property (Essentials Series)
Essentials of Intellectual Property (Essentials Series)

ESSENTIALS OF INTELLECTUAL PROPERTY

Full of valuable tips, techniques, illustrative real-world examples, exhibits, and best practices, this handy and concise paperback will help you stay up to date on the newest thinking, strategies, developments, and technologies in intellectual property.

"Alexander
...


A Companion to Film Comedy
A Companion to Film Comedy

A wide-ranging survey of the subject that celebrates the variety and complexity of film comedy from the ‘silent’ days to the present, this authoritative guide offers an international perspective on the popular genre that explores all facets of its formative social, cultural and political context

  • A wide-ranging...
A Short Course in Digital Photography
A Short Course in Digital Photography
This easy-to-understand book is your guide to getting great photos with your digital camera. It sweeps away unnecessary complexity and explains what you really need to know to use the camera's controls when you're taking pictures. Designed like a text/workbook, there are places for you to write in how to set your camera for the best possible...
The Thermodynamics of Phase and Reaction Equilibria
The Thermodynamics of Phase and Reaction Equilibria

This book provides a sound foundation for understanding abstract concepts of phase and reaction equilibria (e.g. partial molar Gibbs energy, fugacity, and activity), and shows how to apply these concepts to solve practical problems using numerous clear examples. It also presents numerical methods necessary for solving real-world problems as...

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