The IGF system pervades the fields of development, linear and cellular growth and metabolism. Not only is the functional integrity of the IGF system crucial for normal linear growth and metabolism, it is also of fundamental importance for normal fetal development. This book consists of a compilation of chapters based on presentations at a symposium entitled ‘IGFs and IGFBPs: Assessment and Therapeutic Benefit’. Highly qualified basic scientists and endocrinologists report new advances in the broad field of IGF physiology and pathophysiology, related to clinical medicine. New and topical areas of the IGF field are covered, focussing particularly on clinically relevant topics related to growth, pediatric and adult growth hormone deficiency, metabolic disorders, diabetes mellitus and neurology. Molecular and developmental defects are discussed, as are the contributions to clinical diagnosis and management of measurement of IGFs and IGFBPs. The therapeutic potential of recombinant human IGFs and IGFBPs in a range of disorders is also covered. The present volume of Endocrine Development will be of particular interest to scientists and clinicians working in IGF and IGF-related fields and to clinicians working in both pediatric and adult endocrinology and metabolism.
Translocations in Solid Tumors
One of the most fruitful areas of research, as judged by the very large numbers of new cancer genes identified, has been the molecular analysis of recurrent chromosomal translocations. The original concept that gave rise to this book was that key scientists involved in the original isolation of the genes involved in each recurrent solid tumor...
Thinking Strategically in Turbulent Times: An Inside View of Strategy Making
An emergent approach to organizational strategy making assumptions that few organizations actually realize the goal of deliberative, top-down strategic planning, and that effective strategy making occurs on a continual basis and is a shared activity of the entire organization. This innovative book provides the first in-depth look at how real...
Engineering Economy (16th Edition) - Standalone book
Engineering Economy is intended to serve as a text for classroom instruction in undergraduate, introductory courses in Engineering Economics. It also serves as a basic reference for use by practicing engineers in all specialty areas (e.g., chemical, civil, computer, electrical, industrial, and mechanical engineering)....
Go: Building Web Applications
Build real-world, production-ready solutions by harnessing the powerful features of Go
About This Book
An easy-to-follow guide that provides everything a developer needs to know to build end-to-end web applications in Go
Write interesting and clever, but simple code, and learn skills and...
Explore the new features added to the core Docker Engine to make multi-container orchestration easy
Leverage tools such as Docker Machine, Swarm, Compose, and third-party tools such as Kubernetes, Mesosphere, and CoreOS to orchestrate containers
Use Docker Compose with Swarm and