Home | Amazing | Today | Tags | Publishers | Years | Account | Search 
Iron Metabolism: From Molecular Mechanisms to Clinical Consequences

Buy

Iron is of fundamental importance to the growth, development and well-being of almost all living organisms. Multiple biological systems have evolved for the uptake, utilisation, storage, and homeostasis of iron in microbes, plants and mammals. Both iron deficiency and iron overload are found extensively in humans; the intimate links between iron and oxidative stress are associated with a wide range of pathologies. Iron has a well established role in infections by a range of microorganisms and parasites. Other metals such as copper and zinc are also closely linked with iron metabolism. Iron overloads and deficiencies are important factors in the health of humans and are therefore a key target in drug development.

Iron Metabolism: From Molecular Mechanisms to Clinical Consequences, 3rd Edition presents a comprehensive overview of this important field.Topics covered include:

  • Solution chemistry of iron in biological media
  • The importance of iron for biological systems
  • Microbial iron transport and metabolism
  • Iron uptake by plants and fungi
  • Cellular iron uptake and export in mammals
  • Intracellular iron storage and biomineralization
  • Intracellular iron metabolism and cellular iron homeostasis
  • Iron absorption in mammals, with particular reference to man, and regulation of systemic iron balance
  • Pathophysiology of iron deficiency and iron overload in man
  • Iron and oxidative stress
  • Brain iron homeostasis and its perturbation in various neurodegenerative diseases
  • Interactions between iron and other metals

Written in a lively style by one of the leaders in the field and presented in full colour, this third, expanded edition of Iron Metabolism has been fully updated with the latest discoveries. Major additions include recent information on mitochondrial iron metabolism and the role of frataxin; transcriptional control of iron homeostasis; orally active iron chelators; the roles of hepcidin and erythropoietin; the increasing number of types of iron overload; and the importance of iron in Alzheimer’s disease. 

Iron Metabolism is essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and the medical sciences.  It will also find space on the bookshelves of bioinorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, and pharmacologists in the pharmaceutical industry interested in developing novel iron-binding drugs.

(HTML tags aren't allowed.)

How to Do Everything Microsoft SharePoint 2010
How to Do Everything Microsoft SharePoint 2010

Master Microsoft SharePoint 2010

In How to Do Everything: Microsoft SharePoint 2010, Stephen Cawood--a former member of the SharePoint development team--explains how to get the most out of this powerful business collaboration platform. Learn how to use document management functions, wikis, taxonomy, blogs, My Sites, web...

Crystal Reports 10 For Dummies
Crystal Reports 10 For Dummies
Sample reports and more on companion Web site

Create simple or sophisticated reports, add elements, format, and deliver them

What good is all that data you’re keeping if you can’t put it in a form that means something? This handy guide gets you going with Crystal Reports 10 and its exciting enterprise enhancements. Let...

Linux Operations and Administration
Linux Operations and Administration

LINUX OPERATIONS AND ADMINISTRATION introduces readers to Linux operations and system administration through a unified installation, using virtual machines. This text is more effective than those that take a professional approach because it eliminates confusion from working with differing hardware configurations, while allowing users to test...


Applied Natural Language Processing with Python: Implementing Machine Learning and Deep Learning Algorithms for Natural Language Processing
Applied Natural Language Processing with Python: Implementing Machine Learning and Deep Learning Algorithms for Natural Language Processing
Learn to harness the power of AI for natural language processing, performing tasks such as spell check, text summarization, document classification, and natural language generation. Along the way, you will learn the skills to implement these methods in larger infrastructures to replace existing code or create new...
Computer Games and Team and Individual Learning
Computer Games and Team and Individual Learning

Documents research on the impact of computer games on the learning of adults. Computer games and learning are characterized from a series of different theoretical and empirical viewpoints. Both civilian sector and military applications are presented. While effectiveness of game environments to support learning can be documented in terms of...

Software Development on the SAP HANA Platform
Software Development on the SAP HANA Platform

Written by a SAP HANA expert, this book takes you from installation to running your own processes in no time. By the end of the course you'll have awesome data retrieval and analytical powers to call on.

Overview

  • Learn SAP HANA from an expert
  • Go from installation and setup to running...
©2019 LearnIT (support@pdfchm.net) - Privacy Policy