The sixth edition of the Manual of Nephrology continues to focus on the practical clinical aspects of the diagnosis and management of patients with electrolyte and acid-base disorders, urinary tract infections, kidney stones, glomerulonephritis and vasculitis, acute or chronic renal failure, hypertension, kidney disease and hypertension in pregnancy, and drug dosing with renal impairment. Because of the growing number of patients with end stage renal disease (ESRD), separate chapters are now included on treatment by chronic renal replacement therapy with dialysis and kidney transplantation. The Manual of Nephrology should continue to be of excellent clinical value for those caregivers encountering patients with the above disorders. This would include house officers, medical students, primary care physicians, nephrology fellows, nurse practitioners, and busy subspecialists outside of nephrology.
I am very appreciative of the outstanding contributions by the authors who have made every effort to update each chapter with recent advances in the diagnosis and management of the spectrum of hypertensive and kidney disorders. This includes adding several new authors who are outstanding clinician-educators. The Manual of Nephrology is again dedicated to Professor Hugh de Wardener who has made enormous contributions to the fields of hypertension and nephrology as a clinician, scientist, and educator for over 60 years.