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Mass Spectrometry and Genomic Analysis

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The human genome project is set to revolutionise health care and medicine in the near future. The genetic make up of each individual gives clues as to the genetic factors that predispose one to a particular genetic disease. Single Nucleotide Polymorphisms (SNPs), single base changes in the nucleotide DNA sequence of individuals, are thought to be the main cause of genetic variation. By comparing patterns of SNP allele frequencies between disease affected and control populations, disease associated SNPs can be identified and potential disease gene(s) located. These types of study necessitate genotyping of thousands of SNPs which requires the use of powerful, high throughput, systems of analysis. Mass spectrometry is fast becoming the preferred technology for this type of high throughput analysis. This book contains a collection of descriptions of some of the most outstanding advances in the field of mass spectrometry from which, I hope, the reader will be able to learn both the principles and the most up to date methods for its use in genomic analysis. It covers the general principles of the technologies and more in depth detailed descriptions for more academic reading and information. Audience: Whether you are a student, a post-doctoral researcher or experienced MS user, this book will be a stimulating addition to the analytical arena of mass spectrometry and genomic analysis.
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SAP Transaction Codes: Frequently Used T-Codes
SAP Transaction Codes: Frequently Used T-Codes

SAPTransaction Codes: Frequently Used T-Codes is a reference book, which will be a handy tool for those using the SAP business software. It can be used by casual end users, power/super users, subject matter experts (SMEs) implementation project team members, as well application support staff.

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Geometric Spanner Networks
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Aimed at an audience of researchers and graduate students in computational geometry and algorithm design, this book uses the Geometric Spanner Network Problem to showcase a number of useful algorithmic techniques, data structure strategies, and geometric analysis techniques with many applications, practical and theoretical. The authors present...
Microsoft Visual C++ .NET Step by Step - Version 2003
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Teach yourself the latest version of Visual C++--and begin developing for Microsoft .NET—one step at a time. This practical, hands-on tutorial expertly guides you through the fundamentals—from writing managed code to running and debugging your first .NET-based applications and XML Web services. Work at your own pace through...


Network Security Principles and Practices
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Expert solutions for securing network infrastructures and VPNs.

  • Build security into the network by defining zones, implementing secure routing protocol designs, and building safe LAN switching environments

  • Understand the inner...

Research-Based Web Design & Usability Guidelines
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U.S. Department of Health and Human Services’ (HHS) Research-Based Web Design and Usability Guidelines. These Guidelines reflect HHS’ commitment to identifying innovative, research-based approaches that result in highly responsive and easy-to-use Web sites for the public.

The Federal government is the largest single producer,
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Higher-Level Hardware Synthesis
Higher-Level Hardware Synthesis
In the mid 1960s, when a single chip contained an average of 50 transistors,
Gordon Moore observed that integrated circuits were doubling in complexity
every year. In an influential article published by Electronics Magazine in 1965,
Moore predicted that this trend would continue for the next 10 years. Despite
being criticized
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