Enzyme kinetics, binding kinetics and pharmacological dose-response curves are currently analyzed by a few standard methods. Some of these, like Michaelis-Menten enzyme kinetics, use plausible approximations, others, like Hill equations for dose-response curves, are outdated. Calculating realistic reaction schemes requires numerical mathematical routines which usually are not covered in the curricula of life science. This textbook will give a step-by-step introduction to numerical solutions of non-linear and differential equations. It will be accompanied with a set of programs to calculate any reaction scheme on any personal computer. Typical examples from analytical biochemistry and pharmacology can be used as versatile templates. When a reaction scheme is applied for data fitting, the resulting parameters may not be unique. Correlation of parameters will be discussed and simplification strategies will be offered.
High Performance Switches and Routers
Learn to Design High Performance Switches and Routers for Today's Ever Growing Internet Traffic
As Internet traffic continues to grow, and demands for quality of service become more stringent, researchers and engineers can turn to High Performance Switches and Routers for tested and proven solutions. This...
Privacy Online: Perspectives on Privacy and Self-Disclosure in the Social Web
Privacy is a basic human need, and losing privacy is perceived as an extremely
threatening experience. Privacy embraces solitude, personal space, or intimacy with
family and friends and as such, it is a ubiquitous and trans-cultural phenomenon.
Privacy leverages well-being; without privacy we are at risk of becoming physically
Software Business: First International Conference, ICSOB 2010
This book contains the refereed proceedings of the First International Conference on Software Business (ICSOB) in Jyväskylä, Finland, in June 2010. This inaugural conference brought together a strong international community from 17 countries from the Americas, Europe, India and Australia with research disciplines from various fields...
Semi-Supervised Learning (Adaptive Computation and Machine Learning) In the field of machine learning, semi-supervised learning (SSL) occupies the middle ground, between supervised learning (in which all training examples are labeled) and unsupervised learning (in which no label data are given). Interest in SSL has increased in recent years, particularly because of application domains in which unlabeled data are... Pomodoro Technique Illustrated: Can You Focus - Really Focus - for 25 Minutes?
You have so much you need to accomplish today. Your list is a mile long and you find yourself getting interrupted every other minute. You'd like to tell everyone to leave you alone, but most of the interruptions are coming from you! You think of a phone call you need to make or a web site you need to check and before you know it...
There's no easier, faster, or more practical way to learn the really tough subjects
McGraw-Hill's Demystified titles are the most efficient, interestingly written, brush-ups you can find. Organized as self-teaching guides, they come complete with key points, background information, questions at the end of each...