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Numerical Methods for the Life Scientist: Binding and Enzyme Kinetics Calculated with GNU Octave and MATLAB

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Enzyme kinetics, binding kinetics and pharmacological dose-response curves are currently analyzed by a few standard methods. Some of these, like Michaelis-Menten enzyme kinetics, use plausible approximations, others, like Hill equations for dose-response curves, are outdated. Calculating realistic reaction schemes requires numerical mathematical routines which usually are not covered in the curricula of life science. This textbook will give a step-by-step introduction to numerical solutions of non-linear and differential equations. It will be accompanied with a set of programs to calculate any reaction scheme on any personal computer. Typical examples from analytical biochemistry and pharmacology can be used as versatile templates. When a reaction scheme is applied for data fitting, the resulting parameters may not be unique. Correlation of parameters will be discussed and simplification strategies will be offered.

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Sensors: Theory, Algorithms, and Applications (Springer Optimization and Its Applications)
Sensors: Theory, Algorithms, and Applications (Springer Optimization and Its Applications)
In recent years, technological advances have resulted in the rapid development of a new exciting research direction – the interdisciplinary use of sensors for data collection, systems analysis, and monitoring. Application areas include military surveillance, environmental screening, computational neuroscience,...
Combinatorial Optimization: Theory and Algorithms (Algorithms and Combinatorics)
Combinatorial Optimization: Theory and Algorithms (Algorithms and Combinatorics)

This comprehensive textbook on combinatorial optimization places special emphasis on theoretical results and algorithms with provably good performance, in contrast to heuristics. It is based on numerous courses on combinatorial optimization and specialized topics, mostly at graduate level. This book reviews the...

Bayesian Networks in R: with Applications in Systems Biology (Use R!)
Bayesian Networks in R: with Applications in Systems Biology (Use R!)
While there have been significant advances in capturing data from the entities across complex real-world systems, their associations and relationships are largely unknown. Associations between the entities may reveal interesting system-level properties that may not be apparent otherwise. Often these associations are hypothesized...

Graphs, Networks and Algorithms (Algorithms and Computation in Mathematics)
Graphs, Networks and Algorithms (Algorithms and Computation in Mathematics)

This is the third edition of the classic textbook on the subject. With its clear writing, strong organization, and comprehensive coverage of essential theory it is like a personal guide through this important topic, and now has lots of extra material.

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Computational Geometry: Algorithms and Applications, Second Edition
Computational Geometry: Algorithms and Applications, Second Edition
This well-accepted introduction to computational geometry is a textbook for high-level undergraduate and low-level graduate courses. The focus is on algorithms and hence the book is well suited for students in computer science and engineering. Motivation is provided from the application areas: all solutions and techniques from computational...
JavaScript Step by Step (Step by Step Developer)
JavaScript Step by Step (Step by Step Developer)

Your hands-on guide to JavaScript fundamentals

Expand your expertise—and teach yourself the fundamentals of JavaScript. If you have previous programming experience but are new to JavaScript, this tutorial delivers the step-by-step guidance and coding exercises you need to master core topics and...

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