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Prevention of Coronary Heart Disease: From the Cholesterol Hypothesis to w6/w3 Balance Contributions by Okuyama, H. (Nagoya); Ichikawa, Y. (Nagoya); ... Review of Nutrition and Dietetics, Vol. 96)

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This publication is organized in an exceptional way: Each chapter introduces several completed clinical trials and provides the original conclusions and discussions of the results. The authors then contribute their own comments and interpretations of the findings, challenging the prevailing belief that serum cholesterol is a mediator of disease which is increased by eating saturated fats and decreased by eating polyunsaturated fats. They argue that upon closer scrutiny, the diet recommendations based on the cholesterol hypothesis are essentially ineffective in reducing serum cholesterol levels in the long run. Instead, it is proposed that traditional cholesterol biomarkers are of different significance in short- and long-term interventions due to the feedback control mechanisms in the body. Even more important, the association of high serum cholesterol values with high coronary heart disease mortality is not consistent when different populations are compared: This mortality rate may simply reflect the incidence and severity of familial hypercholesterolemia cases. This agrees with the observation that higher serum cholesterol values associate with lower cancer and all-cause mortalities in populations with a low relative proportion of this disorder. Thus, there seems to be no benefit of limiting dietary cholesterol intake or lowering serum cholesterol values below a certain limit. Moreover, evidence has been found that the health risk results from high intakes of calories, aggravated by an unbalanced intake of omega6/omega3 polyunsaturated fats. Based on the reviewed data, new directions of lipid nutrition are recommended for the primary and secondary prevention of coronary heart disease, cancer and all-cause deaths, which will likely revolutionize current dietary practice.

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Symbolic and Quantitative Approaches to Reasoning with Uncertainty: 11th European Conference
Symbolic and Quantitative Approaches to Reasoning with Uncertainty: 11th European Conference

This book constitutes the refereed proceedings of the 11th European Conference on Symbolic and Quantitative Approaches to Reasoning with Uncertainty, ECSQARU 2011, held in Belfast, UK, in June/July 2011. The 60 revised full papers presented together with 3 invited talks were carefully reviewed and selected from 108 submissions. The papers are...

The New Shop Class: Getting Started with 3D Printing, Arduino, and Wearable Tech
The New Shop Class: Getting Started with 3D Printing, Arduino, and Wearable Tech

The New Shop Class connects the worlds of the maker and hacker with that of the scientist and engineer. If you are a parent or educator or a budding maker yourself, and you feel overwhelmed with all of the possible technologies, this book will get you started with clear discussions of what open source technologies like 3D printers,...

Real-World Hadoop
Real-World Hadoop

If you’re a business team leader, CIO, business analyst, or developer interested in how Apache Hadoop and Apache HBase-related technologies can address problems involving large-scale data in cost-effective ways, this book is for you. Using real-world stories and situations, authors Ted Dunning and Ellen Friedman show Hadoop...


Oracle Performance Troubleshooting: With Dictionary Internals SQL & Tuning Scripts (Oracle In-Focus series)
Oracle Performance Troubleshooting: With Dictionary Internals SQL & Tuning Scripts (Oracle In-Focus series)

More than ever before, today's Oracle DBA faces a database farm that is growing both in physical size and actual numbers. To keep these databases up and performing at exceptional levels, the database administrator needs more than a cobbled together set of scripts that they use to (hopefully) verify that everything is in order.

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Chromatographic Detectors (Chromatographic Science Series)
Chromatographic Detectors (Chromatographic Science Series)

Written by a seasoned chromatographer with more that 40 years, experience in the field, this reference comprehensively covers the design, construction, and operation of gas chromatography (GC), liquid chromatography (LC), and thin-layer chromatography (TLC) detectors--all in one convenient, up-to-date source.

The development of...

20: Dental Erosion: From Diagnosis to Therapy (Monographs in Oral Science, Vol. 20)
20: Dental Erosion: From Diagnosis to Therapy (Monographs in Oral Science, Vol. 20)
Dental Erosion: A challenge for the 21st century! This monograph offers a guide towards better oral health in the future. Erosive tooth wear is a multifactorial condition of growing concern to the clinician and the subject of extensive research – a view supported by the literature and impressions from many international...
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