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Protein Tyrosine Phosphatase Control of Metabolism

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Although phosphorylation of proteins on tyrosine is relatively rare compared to phosphorylation on serine or threonine residues, the past two decades of research into PTP function have led to a great appreciation of the critical role PTPs have in regulating basic cellular processes. Among these important roles is the regulation of cellular signaling pathways related to metabolism. This volume contains chapters which highlight many aspects of PTP function in the context of metabolism. Given the growing obesity and diabetes epidemics in the United States and throughout the world, the desire to identify possible therapeutic targets for treatment of these diseases is a high priority. In many ways, PTPs may be attractive drug targets since they are amenable to targeting with small molecules; however many challenges abound in making PTP inhibitors.

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Blockchain Basics: A Non-Technical Introduction in 25 Steps
Blockchain Basics: A Non-Technical Introduction in 25 Steps

In 25 concise steps, you will learn the basics of blockchain technology. No mathematical formulas, program code, or computer science jargon are used. No previous knowledge in computer science, mathematics, programming, or cryptography is required. Terminology is explained through pictures, analogies, and metaphors.

This book...

Maya 2008 Character Modeling & Animation: Principles and Practices
Maya 2008 Character Modeling & Animation: Principles and Practices
Are you ready to take on the challenge of animating realistic and compelling characters using the latest version of Maya, the powerful 3D graphics and modeling software? "Maya® 2008 Character Modeling and Animation: Principles and Practices" shows beginner to intermediate animation students and enthusiasts how to create...
Agile Software Development: The Cooperative Game (2nd Edition)
Agile Software Development: The Cooperative Game (2nd Edition)

“Agile Software Development is a highly stimulating and rich book. The author has a deep background and gives us a tour de force of the emerging agile methods.”

–Tom Gilb

 

The agile model of...


IP Networking over Next-Generation Satellite Systems: International Workshop, Budapest, July 2007
IP Networking over Next-Generation Satellite Systems: International Workshop, Budapest, July 2007
With the boom of Internet, IP-based applications, such as WWW and multimedia, bave been an essential part of our life, and there is an ever-increasing demand for accessing high-speed Internet services anywhere and anytime. This trend unavoidably has huge impacts on the design of the next-generation satellite systems. On the other hand, with its...
SAP ERP Financials and FICO Handbook
SAP ERP Financials and FICO Handbook

This up-to-date quick reference guide helps the reader through the most popular SAP module. It includes material on SAP ERP Financials, SAP FICO, and SAP R/3. Unlike most books that only provide questions and answers for certification or interview preparation, this book covers fifty common business situations related to ERP Financials/FICO...

Human and Nonhuman Bone Identification: A Color Atlas
Human and Nonhuman Bone Identification: A Color Atlas
When someone presents a bone (or series of bones) to a forensic anthropologist for identification, deciding whether or not the bone is human is one of the first steps in determining its importance in a medicolegal investigation.  Almost every forensic anthropologist has been asked to drop everything and go to a scene that has been secured by...
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