Home | Amazing | Today | Tags | Publishers | Years | Account | Search 
Synthetic Nucleic Acids as Inhibitors of Gene Expression: Mechanisms, Applications, and Therapeutic Implications

Buy

In the post-genomic era we have, at our fingertips, an incredible array of genomic sequences from a multitude of complex organisms. There remains, however, the critical need to understand the precise roles individual genes play in complex biological milieu. Synthetic nucleic acids are at the cutting-edge of molecular strategies that target genes of interest in a specific, efficient and cost-effective manner. These tools are now being used as new and exciting gene-silencing agents in vitro, in a panoply of animal models, and as novel therapeutics in human disease.

Synthetic Nucleic Acids as Inhibitors of Gene Expression: Mechanisms, Applications, and Therapeutic Implications brings together timely, authoritative reviews by renowned international leaders in the fields of ribozymes, RNA interference, DNAzymes and oligonucleotide decoys, with emphasis on biochemistry and translational research. The chapters on ribozymes include discussions of ribozyme subtypes, structure-function aspects, and therapeutic applications. This is followed by a comprehensive discussion of DNAzymes, their various subtypes, kinetics and biochemistry, and applications in target validation. Finally, the mechanisms and multiple therapeutic applications of double-stranded oligonucleotide decoys are described.

For readers ranging from graduate students to researchers seeking target validation for pharmaceuticals to clinicians seeking innovative cancer and cardiovascular therapies, no resource is more complete and up to date than Synthetic Nucleic Acids as Inhibitors of Gene Expression: Mechanisms, Applications and Therapeutic Implications.

(HTML tags aren't allowed.)

JavaScript 1.5 by Example
JavaScript 1.5 by Example
JavaScript 1.5 by Example starts with a taste of JavaScript – what it is, what it's for, and what readers need to get started. The book then explains how to add JavaScript to existing HTML pages, leading readers into the fundamentals of the language including JavaScript syntax, notation and conventions, communicating with users via input and...
Noise Sources in Turbulent Shear Flows: Fundamentals and Applications (CISM International Centre for Mechanical Sciences)
Noise Sources in Turbulent Shear Flows: Fundamentals and Applications (CISM International Centre for Mechanical Sciences)

The articles in this volume present the state-of-the-art in noise prediction, modeling and measurement. The articles are partially based on class notes provided during the course `Noise sources in turbulent shear flows', given at CISM on April 2011. The first part contains general concepts of aero acoustics, including vortex sound theory...

Excel for Scientists and Engineers: Numerical Methods
Excel for Scientists and Engineers: Numerical Methods
Learn to fully harness the power of Microsoft Excel® to perform scientific and engineering calculations

With this text as your guide, you can significantly enhance Microsoft Excel's® capabilities to execute the calculations needed to solve a variety of chemical, biochemical, physical, engineering, biological, and medicinal problems. The...


Microsoft Expression Web 2 On Demand
Microsoft Expression Web 2 On Demand
Welcome to Microsoft Expression Web 2 On Demand, a visual quick reference book that shows you how to work efficiently with Expression Web 2. This book provides complete coverage of basic to advanced Expression Web 2 skills.

How This Book Works

You don't have to read this book in any
...
DarkMarket: Cyberthieves, Cybercops and You
DarkMarket: Cyberthieves, Cybercops and You

"This extraordinarily powerful book demonstrates how utterly we lack the shared supranational tools needed to fight cybercrime. Essential reading." --Roberto Saviano, author of Gommorah

The benefits of living in a digital, globalized society are enormous; so too are the dangers. The world has become a
...

The Unofficial Guide to Managing Rental Property
The Unofficial Guide to Managing Rental Property
Whether you own a single-family home, a duplex,
a triplex, or multiple units, if you rent it out, you’re a
landlord. And as a landlord, you need good information.
This book begins with the basics and takes you
through many different steps along the way. Aimed
primarily at landlords just getting into the business,...
©2019 LearnIT (support@pdfchm.net) - Privacy Policy