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This book, the first complete textbook on this novel field in Medicine, comprehensively covers the clinical presentation, pathogenesis, genetics, and latest management strategies for autoinflammatory disorders as well as the basic science of autoinflammation. Relevant concepts such as how translational science of genetics and immunology relates to the innate immune system and autoinflammation are covered. Descriptions of the monogenic and polygenic/complex diseases that fall under the umbrella of autoinflammatory diseases are provided. Further topics covered include the latest clinical and genetic diagnostic approaches, concepts on the relationship between autoinflammation and autoimmunity/immunodeficiency, the role of autoinflammation in cancer, treatments and management strategies for these diseases, and potential areas of future development.
The Textbook of Autoinflammation systematically describes and reviews diagnostic and treatment options for autoinflammatory disorders as well as all aspects of the concept of autoinflammation, and represents a valuable resource for professionals in a variety of disciplines who encounter these patients or who study autoinflammation.
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 A Structural Account of MathematicsCharles Chihara's new book develops and defends a structural view of the nature of mathematics, and uses it to explain a number of striking features of mathematics that have puzzled philosophers for centuries. The view is used to show that, in order to understand how mathematical systems are applied in science and everyday life, it is not necessary... | | The SAIC Solution: How We Built an $8 Billion Employee-Owned Technology CompanyFor more than three decades, Science Applications International Corporation (SAIC)—the largest employee-owned research and technology company in the United States—has achieved unparalleled success in the areas of science, engineering, and technology, all while flying well below the radar of most casual business observers.
As the... | | Virtualization for Dummies AMD Special EditionVirtualization is the latest in a long line of technical innovations designed to increase the level of system abstraction and enable IT users to harness ever-increasing levels of computer performance.
At its simplest level, virtualization allows you, virtually and cost-effectively, to have two or more computers, running two or more... |
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