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Tumor Metabolome Targeting and Drug Development (Cancer Drug Discovery and Development)

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In this volume, the major metabolic alterations identified in cancer and tumor-associated cells are explored, including discussions of former and emerging approaches to drug development in targeting cancer cell metabolism.

The metabolic network in cells promotes the generation of both energy and biomass needed for them to grow, divide and differentiate. However, the metabolism of malignant cells generally varies from that of normal cells. These differences provide a platform for the discovery of new approaches to targeting potential vulnerabilities in cancer cells for therapeutic options Some of the significant changes that occur involve ATP production and consumption that modulates the ATP to ADP ratio, hypoxia and the effects of reactive oxygen species on glycolysis, regulation of mitochondrial respiration, induction and suppression of autophagy, and the Warburg effect and “reverse” Warburg effect--these topics and more are discussed in this volume.

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Evolutionary Algorithms and Chaotic Systems (Studies in Computational Intelligence)
Evolutionary Algorithms and Chaotic Systems (Studies in Computational Intelligence)

This book discusses the mutual intersection of two fields of research: evolutionary computation, which can handle tasks such as control of various chaotic systems, and deterministic chaos, which is investigated as a behavioral part of evolutionary algorithms.

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Pro Android Apps Performance Optimization (Professional Apress)
Pro Android Apps Performance Optimization (Professional Apress)
Android quickly became almost ubiquitous. With the world transitioning from feature phones to smartphones, and then discovering that tablets are, after all, devices we can hardly live without, application developers today have a choice between mostly two platforms: Android and iOS. Android lowered, some may even say broke, the...
Managing Your Money All-In-One For Dummies
Managing Your Money All-In-One For Dummies
Want to take control of your finances once and for all? Managing Your Money All-in-One For Dummies combines expert money management with personal finance tips. From credit cards and insurance to taxes, investing, retirement, and more, seven mini-books show you how to improve your relationship with money — no matter your age or stage...

Pattern-Oriented Software Architecture Volume 1: A System of Patterns
Pattern-Oriented Software Architecture Volume 1: A System of Patterns
Represents the progression and evolution of the pattern approach into a system of patterns capable of describing and documenting large-scale applications.

This practical tutorial/reference demonstrates how patterns can enable users to create large-scale applications and solve recurring design problems. Contains a catalog of 25
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CompTIA A+ 220-701 and 220-702 Practice Questions Exam Cram (4th Edition)
CompTIA A+ 220-701 and 220-702 Practice Questions Exam Cram (4th Edition)

Welcome to CompTIA A+ Practice Questions Exam Cram. The sole purpose of this book is to provide you with practice questions that are complete with answers and explanations to help you learn, drill, and review for the CompTIA A+ certification exam. The book offers many questions that will help you practice each exam objective and will help you...

Distributed Systems: Principles and Paradigms
Distributed Systems: Principles and Paradigms

Presents a complete introduction to distributed principles and paradigms. Author identifies the seven key principles of distributed systems, and presents extensive examples of each. For all developers, software engineers, and architects who need an in-depth understanding of distributed systems.

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