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Using Patient-Friendly Composite Endpoints to Measure the Success of Acute Migraine Medications: 4th Annual Migraine Meeting, Budapest, October 2004: Proceedings (European Nephrology)

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In 1999, my colleagues and I performed a study in 7 hospitals in different regions throughout Spain where 305 patients were questioned about their use of antimigraine medications [1] . The patients reported previous use of the following acute agents: analgesics (99%), nonsteroidal antiinfl ammatory drugs (NSAIDs, 69%), ergotamines (54%), and sumatriptan (40%). When questioned about their satisfaction with these agents, a subjective good response was reported by 9% of those who had taken analgesics, 23% of those who had taken NSAIDs, 39% of those who had taken ergotamines, and 63% of those who had taken sumatriptan.

Now, 5 years and many second-generation triptans later, how have things changed in the treatment of acute migraine? The articles in this supplement, based on presentations at the 4th Annual Migraine Meeting, October 15–17, 2004, in Budapest, Hungary, report on advances made in the management of acute migraine.

Dr. Lantéri-Minet describes what patients want from their acute migraine medication, that is, complete freedom from pain, rapid onset of action, no recurrence, and absence of side effects, but explains that, with the underuse of triptans, many patients are not receiving the type of medication that will meet these expectations and leave them satisfi ed. In addition, many individuals with migraine are still unrecognized and do not have a physician’s diagnosis.
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